Corneal Ectasia · A Comprehensive Evaluation · Advanced Treatment & Surgery

Comprehensive Keratoconus Treatment

Keratoconus is a progressive condition in which the cornea gradually thins and steepens into an irregular cone, introducing high-order aberrations that glasses and soft lenses cannot fully correct. Early diagnosis and appropriate staging of treatment can halt progression and preserve options for future vision correction.

— Understanding the Disease

What is Keratoconus?

The cornea accounts for approximately two-thirds of the eye's refractive power. Its structural integrity depends on a precisely organised network of collagen fibres within the stroma. In keratoconus, these fibres progressively weaken — allowing the corneal apex to thin and bow forward into an irregular, cone-like shape.

The resulting irregular astigmatism and high-order aberrations distort vision in ways that conventional spectacles cannot neutralise. As disease advances, even rigid gas-permeable and scleral contact lenses may provide diminishing correction. Left untreated, keratoconus may progress to a point where corneal transplantation is the only remaining option.

The condition typically presents in the second or third decade of life. Rate of progression is unpredictable — making early detection and regular topographic monitoring essential for all patients with confirmed or suspected disease.

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Mild — Forme Fruste

Subclinical topographic changes. Vision correctable with spectacles. Monitor closely; CXL if progression documented.

Moderate

Increasing irregular astigmatism. Spectacles inadequate; RGP or scleral lenses needed. CXL to arrest progression.

Mild — Forme Fruste

Significant cone formation. Contact lens tolerance reduced. Reshaping procedures may improve contact lens fit after CXL.

Severe / Hydrops

Dense apical scarring or acute hydrops. May require DALK or PKP if transplant criteria met.

— Spectrum of Treatment

Four Stages of Keratoconus Management

— Halt Progression

Corneal Cross-Linking (CXL)

The only treatment demonstrated to stop Keratoconus from progressing.
Offered in two protocols: epithelium-off (Dresden) and EpiOxa epithelium-on.

Corneal cross-linking stabilize the cornea and preserve all future correction options.

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— Advanced Disease

Corneal Transplant Surgery

Surgery to replace a cornea with severely diseased keratoconus, with a new, healthy, clear cornea. Primary techniques are Deep Anterior Lamellar Keratoplasty (DALK) and Penetrating Keratoplasty (PKP).

The entire corneal stroma is removed and replaced with this surgery.

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— Improve Corneal Shape

Corneal Reshaping

For patients with irregular astigmatism after corneal stabilization with CXL.

Options include:

—> CAIRS Customized Corneal Allogenic Intrastromal Ring Segments,

—> Combined Topography-Guided PRK with CXL (Athens Protocol or TOPOLink Protocol).

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— Coexisting Cataract

Cataract Surgery with Keratoconus

Specialized biometry, IOL selection, and surgical planning are required in eyes with keratoconus. The Apthera IC8 Small Aperture IOL is a well-suited option, providing an extended depth of focus less dependent on centration in an irregular cornea.

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— Keratoconus

Comprehensive Keratoconus Management
& a personalized treatment plan

A keratoconus evaluation with Dr. Hu includes corneal topography with Scheimpflug imaging, wavefront analysis, and pachymetry — followed by an honest discussion of where you are in the disease spectrum and which treatment options are appropriate.

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